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ATXN10/SCA10 Antibody

ATXN10/SCA10 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameATXN10/SCA10 Primary Polyclonal Antibody
Also known asATXN10/SCA10 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenATXN10/SCA10
SpecificityThis is a highly specific antibody against ATXN10/SCA10
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATXN10/SCA10
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A loss of ataxin-10 in primary neuronal cells causes increased apoptosis of cerebellar neurons, Ataxin-10 interacts with p110, Ataxin-10 is a cytoplasmic protein that belongs to the family of armadillo repeat proteins, SCA is caused by the expansion of a translated CAG repeat, SCA10 is caused by an expansion of an ATTCT pentanucleotide repeat in intron 9 of the ataxin-10 gene, Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant disorder that causes cerebellar ataxia and seizures, The ataxin proteins are ubiquitously expressed in nervous tissue, an O-Linked beta-N-acetylglucosamine transferase, and may be important in the regulation of intracellular glycosylation levels and homeostasis in the brain, brain stem and spinal cord in the central nervous system, but are primarily detected in cerebellum, encoding a polyglutamine tract in SCA gene products, known as ataxins, Spinocerebellar ataxia (SCA) is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ATX10_HUMAN, Ataxin-10, Atxn10, Brain protein E46 homolog, E46L, FLJ37990, HUMEEP, Like mouse brain protein E46, SCA10, Spinocerebellar ataxia 10, Spinocerebellar ataxia type 10 protein, Ataxin 10
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetATXN10/SCA10
Short nameATXN10/SCA10 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameATXN10/SCA10 (Antibody to)
Alternative techniqueantibodies
Identity 10549
Gene ATXN10
Long gene name ataxin 10
Synonyms gene SCA10
Synonyms gene name spinocerebellar ataxia 10
Synonyms E46L FLJ37990
Locus 22q13, 31
Discovery year 1999-04-16
GenBank acession AK095309
Entrez gene record 25814
Pubmed identfication 9973298
RefSeq identity NM_013236
Classification Ataxins
Havana BLAST/BLAT OTTHUMG00000150451

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