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ATXN10/SCA10 Antibody, ALEXA FLUOR 488

ATXN10/SCA10 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, ATXN10/SCA10 Polyclonal Antibody
Also known asAnti-ATXN10/SCA10 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenATXN10/SCA10
SpecificityThis is a highly specific antibody against ATXN10/SCA10
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATXN10/SCA10
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen A loss of ataxin-10 in primary neuronal cells causes increased apoptosis of cerebellar neurons, Ataxin-10 interacts with p110, Ataxin-10 is a cytoplasmic protein that belongs to the family of armadillo repeat proteins, SCA is caused by the expansion of a translated CAG repeat, SCA10 is caused by an expansion of an ATTCT pentanucleotide repeat in intron 9 of the ataxin-10 gene, Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant disorder that causes cerebellar ataxia and seizures, The ataxin proteins are ubiquitously expressed in nervous tissue, an O-Linked beta-N-acetylglucosamine transferase, and may be important in the regulation of intracellular glycosylation levels and homeostasis in the brain, brain stem and spinal cord in the central nervous system, but are primarily detected in cerebellum, encoding a polyglutamine tract in SCA gene products, known as ataxins, Spinocerebellar ataxia (SCA) is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms E46L FLJ37990
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ATXN10/SCA10 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetATXN10/SCA10
Short nameATXN10/SCA10 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, ATXN10/SCA10 (Antibody to)
Alternative techniqueantibodies
Identity 10549
Gene ATXN10
Long gene name ataxin 10
Synonyms gene SCA10
Synonyms gene name spinocerebellar ataxia 10
Locus 22q13, 31
Discovery year 1999-04-16
GenBank acession AK095309
Entrez gene record 25814
Pubmed identfication 9973298
RefSeq identity NM_013236
Classification Ataxins
Havana BLAST/BLAT OTTHUMG00000150451

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