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ATXN10/SCA10 Antibody, Cy7 Conjugated

ATXN10/SCA10 Antibody, Cy7 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy7 Conjugated, ATXN10/SCA10 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenATXN10/SCA10
SpecificityThis is a highly specific antibody against ATXN10/SCA10
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human ATXN10/SCA10
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A loss of ataxin-10 in primary neuronal cells causes increased apoptosis of cerebellar neurons, Ataxin-10 interacts with p110, Ataxin-10 is a cytoplasmic protein that belongs to the family of armadillo repeat proteins, SCA is caused by the expansion of a translated CAG repeat, SCA10 is caused by an expansion of an ATTCT pentanucleotide repeat in intron 9 of the ataxin-10 gene, Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant disorder that causes cerebellar ataxia and seizures, The ataxin proteins are ubiquitously expressed in nervous tissue, an O-Linked beta-N-acetylglucosamine transferase, and may be important in the regulation of intracellular glycosylation levels and homeostasis in the brain, brain stem and spinal cord in the central nervous system, but are primarily detected in cerebellum, encoding a polyglutamine tract in SCA gene products, known as ataxins, Spinocerebellar ataxia (SCA) is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms E46L FLJ37990
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetATXN10/SCA10 Conjugated
Short name Conjugated, ATXN10/SCA10 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, ATXN10/SCA10 (Antibody to)
Alternative techniqueantibodies
Identity 10549
Gene ATXN10
Long gene name ataxin 10
Synonyms gene SCA10
Synonyms gene name spinocerebellar ataxia 10
Locus 22q13, 31
Discovery year 1999-04-16
GenBank acession AK095309
Entrez gene record 25814
Pubmed identfication 9973298
RefSeq identity NM_013236
Classification Ataxins
Havana BLAST/BLAT OTTHUMG00000150451

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