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ATXN10/SCA10 Antibody, FITC Conjugated

ATXN10/SCA10 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, ATXN10/SCA10 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenATXN10/SCA10
SpecificityThis is a highly specific antibody against ATXN10/SCA10
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human ATXN10/SCA10
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A loss of ataxin-10 in primary neuronal cells causes increased apoptosis of cerebellar neurons, Ataxin-10 interacts with p110, Ataxin-10 is a cytoplasmic protein that belongs to the family of armadillo repeat proteins, SCA is caused by the expansion of a translated CAG repeat, SCA10 is caused by an expansion of an ATTCT pentanucleotide repeat in intron 9 of the ataxin-10 gene, Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant disorder that causes cerebellar ataxia and seizures, The ataxin proteins are ubiquitously expressed in nervous tissue, an O-Linked beta-N-acetylglucosamine transferase, and may be important in the regulation of intracellular glycosylation levels and homeostasis in the brain, brain stem and spinal cord in the central nervous system, but are primarily detected in cerebellum, encoding a polyglutamine tract in SCA gene products, known as ataxins, Spinocerebellar ataxia (SCA) is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms E46L FLJ37990
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetATXN10/SCA10 Conjugated
Short name FITC Conjugated, ATXN10/SCA10 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, ATXN10/SCA10 (Antibody to)
Alternative techniqueantibodies
Identity 10549
Gene ATXN10
Long gene name ataxin 10
Synonyms gene SCA10
Synonyms gene name spinocerebellar ataxia 10
Locus 22q13, 31
Discovery year 1999-04-16
GenBank acession AK095309
Entrez gene record 25814
Pubmed identfication 9973298
RefSeq identity NM_013236
Classification Ataxins
Havana BLAST/BLAT OTTHUMG00000150451

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