Name : ATXN3L Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6868073375
| Long name | ALEXA FLUOR 594 Conjugated, ATXN3L Polyclonal Antibody |
| Also known as | Anti-ATXN3L PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ATXN3L |
| Specificity | This is a highly specific antibody against ATXN3L |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATXN3L |
| Gene ID Number | 92552 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Longer expansions result in earlier onset and more severe clinical manifestations of the disease, Patients show progressive incoordination of gait and often poor coordination of hands, SCA3 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders, The molecular defect in SCA3 is the a CAG repeat expansion in ATXN3 coding region, also known as Machado-Joseph disease (MJD), bulbar and extrapyramidal signs, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord, ophthalmoplegia, peripheral neuropathy and dementia, speech and eye movements, Defects in ATXN3 are the cause of spinocerebellar ataxia type 3 (SCA3) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | MJDL |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | ATXN3L |
| Short name | ATXN3L Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, ATXN3L (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24173 |
| Gene | ATXN3L |
| Long gene name | ataxin 3 like |
| Synonyms gene name | ataxin 3-like |
| Locus | Xp22, 2 |
| Discovery year | 2004-08-20 |
| Entrez gene record | 92552 |
| RefSeq identity | NM_001135995 |
| Classification | MJD deubiquinating enzymes |
| Havana BLAST/BLAT | OTTHUMG00000021146 |
| Locus Specific Databases | Mental Retardation database |