ATXN3L Antibody, Biotin Conjugated

ATXN3L Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, ATXN3L Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	ATXN3L
Specificity	This is a highly specific antibody against ATXN3L
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human ATXN3L
Gene ID number	92552
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Longer expansions result in earlier onset and more severe clinical manifestations of the disease, Patients show progressive incoordination of gait and often poor coordination of hands, SCA3 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders, The molecular defect in SCA3 is the a CAG repeat expansion in ATXN3 coding region, also known as Machado-Joseph disease (MJD), bulbar and extrapyramidal signs, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord, ophthalmoplegia, peripheral neuropathy and dementia, speech and eye movements, Defects in ATXN3 are the cause of spinocerebellar ataxia type 3 (SCA3)
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	MJDL
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	ATXN3L Conjugated
Short name	Conjugated, ATXN3L Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, ATXN3L (Antibody to)
Alternative technique	antibodies
Identity	24173
Gene	ATXN3L
Long gene name	ataxin 3 like
Synonyms gene name	ataxin 3-like
Locus	Xp22, 2
Discovery year	2004-08-20
Entrez gene record	92552
RefSeq identity	NM_001135995
Classification	MJD deubiquinating enzymes
Havana BLAST/BLAT	OTTHUMG00000021146
Locus Specific Databases	Mental Retardation database

ATXN3L Antibody, Biotin Conjugated

ATXN3L Antibody, Biotin Conjugated size: 0.1ml 333

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