Name : ATXN3L Antibody, Cy5.5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN8210649923
| Long name | Cy5, 5 Conjugated, ATXN3L Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ATXN3L |
| Specificity | This is a highly specific antibody against ATXN3L |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human ATXN3L |
| Gene ID number | 92552 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Longer expansions result in earlier onset and more severe clinical manifestations of the disease, Patients show progressive incoordination of gait and often poor coordination of hands, SCA3 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders, The molecular defect in SCA3 is the a CAG repeat expansion in ATXN3 coding region, also known as Machado-Joseph disease (MJD), bulbar and extrapyramidal signs, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord, ophthalmoplegia, peripheral neuropathy and dementia, speech and eye movements, Defects in ATXN3 are the cause of spinocerebellar ataxia type 3 (SCA3) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | MJDL |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | ATXN3L Conjugated |
| Short name | Conjugated, ATXN3L Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, ATXN3L (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24173 |
| Gene | ATXN3L |
| Long gene name | ataxin 3 like |
| Synonyms gene name | ataxin 3-like |
| Locus | Xp22, 2 |
| Discovery year | 2004-08-20 |
| Entrez gene record | 92552 |
| RefSeq identity | NM_001135995 |
| Classification | MJD deubiquinating enzymes |
| Havana BLAST/BLAT | OTTHUMG00000021146 |
| Locus Specific Databases | Mental Retardation database |