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Aurkb Antibody

Aurkb Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAurkb
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the Aurkb antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis Aurkb antibodyis to be used only for research purposes and not for diagnostics
Uniprot #O70126
PurityAntigen affinity
Description Component of the chromosomal passenger complex (CPC), Phosphorylates 'Ser-10' and 'Ser-28' of histone H3 during mitosis, Required for kinetochore localization of BUB1 and SGOL1 (By similarity), The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (By similarity), a complex that acts as a key regulator of mitosis, Aurkb may be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis
ImmunogenA portion of amino acids 84-111 from the mouse protein was used as the immunogen for this Aurkb antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Aurkb antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetAurkb
Short nameAurkb Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameaurora kinase B (Antibody to)
Alternative techniqueantibodies
Identity 11390
Gene AURKB
Long gene name aurora kinase B
Synonyms gene STK12
Synonyms gene name serine/threonine kinase 12
Synonyms Aik2 IPL1 AurB AIM-1 ARK2 STK5 PPP1R48
Synonyms name aurora-B aurora-1 protein phosphatase 1, regulatory subunit 48
Locus 17p13, 1
Discovery year 1999-01-29
GenBank acession AF004022
Entrez gene record 9212
Pubmed identfication 9858806
RefSeq identity NM_004217
Classification Protein phosphatase 1 regulatory subunits Chromosomal passenger complex
Havana BLAST/BLAT OTTHUMG00000108189

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