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AVEN Antibody, Cy7 Conjugated

AVEN Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, AVEN Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAVEN
SpecificityThis is a highly specific antibody against AVEN
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human AVEN
Gene ID number57099
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background AVEN is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9, Disruption of this process has been implicated in a variety of diseases such as cancer, Higher levels of AVEN mRNA are seen in patients with acute leukemia than in control patients, It is thought that AVEN functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and removal of damaged cells, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that AVEN impedes Apaf-1-mediated caspase activation, suggesting that AVEN may be useful as a prognostic indicator in leukemia patients, tissue homeostasis, Apoptosis plays a major role in normal organism development
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms PDCD12
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetAVEN Conjugated
Short name Conjugated, AVEN Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name caspase activation inhibitor (Antibody to), cyanine 7 coupled, apoptosis
Alternative techniqueantibodies
Alternative to gene target AVEN and IDBG-5324 and ENSG00000169857 and 57099, AVEN and IDBG-646114 and ENSBTAG00000044029 and 512666, Aven and IDBG-196731 and ENSMUSG00000003604 and 74268, Plasma membranes, caspase activation inhibitor, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0006915 and apoptotic process and biological process this GO :0012505 and endomembrane system and cellular component this GO :0016020 and membrane and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, apoptosis
Identity 13509
Gene AVEN
Long gene name apoptosis and caspase activation inhibitor
Synonyms name cell death regulator aven programmed cell death 12
Locus 15q14
Discovery year 2002-09-17
GenBank acession AF283508
Entrez gene record 57099
Pubmed identfication 10949025
RefSeq identity NM_020371
Havana BLAST/BLAT OTTHUMG00000129371

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