Filters

Axin1 Antibody

Axin1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAxin1 Primary Polyclonal Antibody
Also known asAxin1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAxin1
SpecificityThis is a highly specific antibody against Axin1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range830-862/862
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Axin1
Gene ID number8312
Swiss ProtO15169
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also component of the AXIN1-HIPK2-TP53 complex which controls cell growth, Controls dorsoventral patterning via two opposing effects, Enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting the degradation of inhibitory SMAD7, Facilitates the phosphorylation of TP53 by HIPK2 upon ultraviolet irradiation, In Wnt signaling, Likely to function as a tumor suppressor, and modulating Wnt-signaling, apoptosis and development, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B, Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AXIN1, Axin-1, Axis inhibition protein 1, PPP1R49, hAxin, AXIN
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAxin1
Short nameAxin1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameaxin 1 (Antibody to)
Alternative techniqueantibodies
Identity 903
Gene AXIN1
Long gene name axin 1
Synonyms PPP1R49
Synonyms name protein phosphatase 1, regulatory subunit 49
Locus 16p13, 3
Discovery year 1998-09-17
GenBank acession AF009674
Entrez gene record 8312
Pubmed identfication 9230313
Classification Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000064930

Similar products

Subscribe to our Newsletter