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Axin1 Antibody, Cy5 Conjugated

Axin1 Antibody, Cy5 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy5 Conjugated, Axin1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAxin1
SpecificityThis is a highly specific antibody against Axin1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range830-862/862
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human Axin1
Gene ID number8312
Swiss ProtO15169
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also component of the AXIN1-HIPK2-TP53 complex which controls cell growth, Controls dorsoventral patterning via two opposing effects, Enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting the degradation of inhibitory SMAD7, Facilitates the phosphorylation of TP53 by HIPK2 upon ultraviolet irradiation, In Wnt signaling, Likely to function as a tumor suppressor, and modulating Wnt-signaling, apoptosis and development, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B, Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms AXIN1, Axin-1, Axis inhibition protein 1, PPP1R49, hAxin, AXIN
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAxin1 Conjugated
Short name Conjugated, Axin1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, axin 1 (Antibody to)
Alternative techniqueantibodies

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