Name : AXL (Tyr698+Tyr702+Tyr703) Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN9153770360
| Long name | ALEXA FLUOR 555 Conjugated, AXL (Tyr698+Tyr702+Tyr703) Antibody |
| Also known as | Anti-AXL Tyr698+Tyr702+Tyr703 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | AXL Tyr698+Tyr702+Tyr703 |
| Specificity | This is a highly specific antibody against AXL Tyr698+Tyr702+Tyr703 |
| Modification | Phosphorylation |
| Modification Site | Tyr698+Tyr702+Tyr703 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human AXL around the phosphorylation site of Tyr698+Tyr702+Tyr703 |
| Gene ID Number | 558 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Although it is similar to other receptor tyrosine kinases, Axl is a chronic myelogenous leukemia associated oncogene and also associated with colon cancer and melanoma, It is involved in the stimulation of cell proliferation, It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors such as vitamin K dependent protein growth arrest specific gene 6, This gene has two different alternatively spliced transcript variants (AXL1 and AXL2), This receptor can also mediate cell aggregation by homophilic binding, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats, The Axl gene is evolutionarily conserved between vertebrate species, The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | UFO JTK11 Tyro7 ARK |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | AXL (Tyr698+Tyr702+Tyr703) |
| Short name | AXL (Tyr698+Tyr702+Tyr703) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, AXL (Tyr698+Tyr702+Tyr703) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 905 |
| Gene | AXL |
| Long gene name | AXL receptor tyrosine kinase |
| Locus | 19q13, 2 |
| Discovery year | 1992-09-15 |
| GenBank acession | M76125 |
| Entrez gene record | 558 |
| Pubmed identfication | 1656220 |
| Classification | Immunoglobulin like domain containing V-set domain containing Fibronectin type III domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT | OTTHUMG00000182727 |