Name : AXL (Tyr698+Tyr702+Tyr703) Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :368
SKU : GEN1261704567
| Long name | Cy3 Conjugated, AXL (Tyr698+Tyr702+Tyr703) Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | AXL Tyr698+Tyr702+Tyr703 |
| Specificity | This is a highly specific antibody against AXL Tyr698+Tyr702+Tyr703 |
| Modification | Phosphorylation |
| Modification site | Tyr698+Tyr702+Tyr703 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human AXL around the phosphorylation site of Tyr698+Tyr702+Tyr703 |
| Gene ID number | 558 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Although it is similar to other receptor tyrosine kinases, Axl is a chronic myelogenous leukemia associated oncogene and also associated with colon cancer and melanoma, It is involved in the stimulation of cell proliferation, It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors such as vitamin K dependent protein growth arrest specific gene 6, This gene has two different alternatively spliced transcript variants (AXL1 and AXL2), This receptor can also mediate cell aggregation by homophilic binding, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats, The Axl gene is evolutionarily conserved between vertebrate species, The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | UFO JTK11 Tyro7 ARK |
| Properties | 1 of the AXL (Tyr698+Tyr702+Tyr703) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | AXL (Tyr698+Tyr702+Tyr703) Conjugated |
| Short name | Conjugated, AXL (Tyr698+Tyr702+Tyr703) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, AXL (Tyr698+Tyr702+Tyr703) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 905 |
| Gene | AXL |
| Long gene name | AXL receptor tyrosine kinase |
| Locus | 19q13, 2 |
| Discovery year | 1992-09-15 |
| GenBank acession | M76125 |
| Entrez gene record | 558 |
| Pubmed identfication | 1656220 |
| Classification | Immunoglobulin like domain containing V-set domain containing Fibronectin type III domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT | OTTHUMG00000182727 |