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AXL (Tyr698+Tyr702+Tyr703) Antibody, FITC Conjugated

AXL (Tyr698+Tyr702+Tyr703) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, AXL (Tyr698+Tyr702+Tyr703) Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAXL Tyr698+Tyr702+Tyr703
SpecificityThis is a highly specific antibody against AXL Tyr698+Tyr702+Tyr703
ModificationPhosphorylation
Modification siteTyr698+Tyr702+Tyr703
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human AXL around the phosphorylation site of Tyr698+Tyr702+Tyr703
Gene ID number558
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Although it is similar to other receptor tyrosine kinases, Axl is a chronic myelogenous leukemia associated oncogene and also associated with colon cancer and melanoma, It is involved in the stimulation of cell proliferation, It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors such as vitamin K dependent protein growth arrest specific gene 6, This gene has two different alternatively spliced transcript variants (AXL1 and AXL2), This receptor can also mediate cell aggregation by homophilic binding, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats, The Axl gene is evolutionarily conserved between vertebrate species, The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms UFO JTK11 Tyro7 ARK
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAXL (Tyr698+Tyr702+Tyr703) Conjugated
Short name FITC Conjugated, AXL (Tyr698+Tyr702+Tyr703) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, AXL (Tyr698+Tyr702+Tyr703) (Antibody to)
Alternative techniqueantibodies
Identity 905
Gene AXL
Long gene name AXL receptor tyrosine kinase
Locus 19q13, 2
Discovery year 1992-09-15
GenBank acession M76125
Entrez gene record 558
Pubmed identfication 1656220
Classification Immunoglobulin like domain containing V-set domain containing Fibronectin type III domain containing Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000182727

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