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b-Catenin Antibody

b-Catenin Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenb-Catenin
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ICC, IHC-F, IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0
Notes Titration of the b-Catenin antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points
Intented useThis b-Catenin antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P35222
PurityAntigen affinity
Description HGF-induced hepatpomegaly, However, In breast ductal neoplasia, In normal tissues, It plays an important role in various aspects of liver biology including liver development (both embryonic and postnatal), The first two catenins that were identified became known as alpha-catenin, a marked redistribution throughout the cytoplasm results in a diffuse cytoplasmic pattern, and beta-catenin, and pathogenesis of liver cancer, b-Catenin binds the cytoplasmic domain of some cadherins as an adherens junction protein, b-catenin is localized to the membrane of epithelial cells, consistent with its role in the cell adhesion complex, in lobular neoplasia, it is usually localized in cellular membranes, liver regeneration following partial hepatectomy, liver zonation, which can bind to beta-catenin and can also bind actin, Catenins are proteins found in complexes with cadherin cell adhesion molecules of animal cells
Immunogen mouse and rat), A synthetic peptide corresponding to the N-terminus of the human protein (MATQADLMELDMAMEPDRK) was used as the immunogen for this b-Catenin antibody (100% homologous in human
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the b-Catenin antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetb-Catenin
Short nameb-Catenin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameb-Catenin (Antibody to)
Alternative techniqueantibodies

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