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B-RAF Antibody

B-RAF Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenB-RAF
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IF, IHC, WB, FACS
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
Notes Titration of the B-RAF antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis B-RAF antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P15056
PurityPurified
Description Drugs that treat cancers driven by BRAF mutations have been developed, The protein is involved in sending signals inside cells, Two of these drugs, Vemurafenib and Dabrafenib are approved by FDA for treatment of late-stage melanoma, [Wiki], which are involved in directing cell growth, with the protein more formally known as serine/threonine-protein kinase B-Raf, BRAF is a human gene
ImmunogenA portion of amino acids 424-453 from the human protein was used as the immunogen for this B-RAF antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot the B-RAF antibody and store frozen at -20 deg, Store at 4oC for up to one month
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetB-RAF
Short nameB-RAF Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameB-RAF (Antibody to)
Alternative techniqueantibodies
Identity 1097
Gene BRAF
Long gene name B-Raf proto-oncogene, serine/threonine kinase
Synonyms gene name v-raf murine sarcoma viral oncogene homolog B
Synonyms BRAF1
Locus 7q34
Discovery year 1991-07-16
GenBank acession M95712
Entrez gene record 673
Pubmed identfication 2284096 1565476
RefSeq identity NM_004333
Classification RAF family Mitogen-activated protein kinase kinase kinases
Havana BLAST/BLAT OTTHUMG00000157457
Locus Specific Databases LRG_299

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