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B7-H3 Antibody / CD276

B7-H3 Antibody / CD276 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH7, with 0, 02% sodium azide, 3, 5 mg/ml in 1X TBS, 5% BSA (US sourced) and 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenB7-H3 / CD276
Host animalGoat (Capra aegagrus hircus)
ClonalityPolyclonal (goat origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA (peptide), WB
Recommended dilutionsELISA (peptide) LOD: 1:8000, Western blot: 1-3ug/ml
NotesOptimal dilution of the B7-H3 antibody should be determined by the researcher
Intented useThis B7-H3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q5ZPR3
PurityAntigen affinity
Description Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy, May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces, May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells, [UniProt], May participate in the regulation of T-cell-mediated immune response
ImmunogenAmino acids KHSDSKEDDGQE were used as the immunogen for this B7-H3 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot and store the B7-H3 antibody at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetB7-H3 / CD276
Short nameB7-H3 Antibody / CD276
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameB7-H3 (Antibody to) / CD276 molecule
Alternative techniqueantibodies
Alternative to gene target CD276 and IDBG-21197 and ENSG00000103855 and 80381, CD276 and IDBG-645646 and ENSBTAG00000019734 and 508656, Cd276 and IDBG-172080 and ENSMUSG00000035914 and 102657, Cell surfaces, protein binding, this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0006955 and immune response and biological process this GO :0008283 and cell proliferation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042110 and T cell activation and biological process this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0045077 and negative regulation of interferon-gamma biosynthetic process and biological process this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045085 and negative regulation of interleukin-2 biosynthetic process and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050776 and regulation of immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :1900042 and positive regulation of interleukin-2 secretion and biological process, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005515: protein binding, this GO :0005515: protein binding, CD276 molecule
Identity 19137
Gene CD276
Long gene name CD276 molecule
Synonyms gene name CD276 antigen
Synonyms B7-H3 B7H3 B7RP-2
Locus 15q24, 1
Discovery year 2005-03-04
GenBank acession AF302102
Entrez gene record 80381
Pubmed identfication 11224528 12055244
RefSeq identity NM_025240
Classification C2-set domain containing CD molecules V-set domain containing
Havana BLAST/BLAT OTTHUMG00000137585

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