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BACE1 Antibody, FITC Conjugated

BACE1 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, BACE1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBACE1
SpecificityThis is a highly specific antibody against BACE1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range451-501/501
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human BACE1
Gene ID number23621
Swiss ProtP56817
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Cleaves at the N-terminus of the A-beta peptide sequence, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, Responsible for the proteolytic processing of the amyloid precursor protein (APP)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetBACE1 Conjugated
Short name FITC Conjugated, BACE1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, BACE1 (Antibody to)
Alternative techniqueantibodies
Identity 933
Gene BACE1
Long gene name beta-secretase 1
Synonyms gene BACE
Synonyms gene name beta-site APP-cleaving enzyme beta-site APP-cleaving enzyme 1
Locus 11q23, 3
Discovery year 1999-10-29
GenBank acession AF190725
Entrez gene record 23621
Pubmed identfication 10531052
Havana BLAST/BLAT OTTHUMG00000160636

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