Name : BACH2 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN1352815658
| Long name | Biotin Conjugated, BACH2 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | BACH2 |
| Specificity | This is a highly specific antibody against BACH2 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human BACH2 |
| Gene ID number | 60468 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | BACH1 and BACH2, BACH1 and BACH2 have significant similarity to each other in BTB domain and Cap â, BACH1 appears ubiquitous, BACH2, BACH2 also plays an important role in the regulation of B cell development, BACH2 heterodimerizes with MAZR through its BTB/POZ domain to activate transcription, BACH2 is localized to the cytoplasm through its C-terminal cytoplasmic localization signal (CLS), In culture cells, MafF, Oxidative stressors aborted the CLS activity and induce nuclear accumulation of BACH2, They dimerize with other proteins and bind DNA to either represse or activate transcription depending on the dimer compositions, a 841 amino acid polypeptide, and MafG) are basic region leucine zipper (bZip) proteins that can function as transcriptional activators or repressors, are members of a novel family of BTB/POZ-basic region leucine zipper (bzip) factors, collar-type bZip domain but are otherwise divergent, heterodimerization partners of MafK, is an Nrf2-related transcription repressor and a tissue-specific partner of the Maf oncoprotein family, neuronal cells and is abundantly expressed in the early stages of B-cell differentiation, whereas BACH2 is restricted to monocytes, which mediates nucleocytoplasmic communciation to couple oxidative stress and transcription repression in mammalian cells, &euro, &euro, &tilde, &trade, Members of the small Maf family (MafK, nâ |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | BTBD25 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | BACH2 Conjugated |
| Short name | Conjugated, BACH2 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, BACH2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 14078 |
| Gene | BACH2 |
| Long gene name | BTB domain and CNC homolog 2 |
| Synonyms gene name | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| Locus | 6q15 |
| Discovery year | 2001-04-27 |
| GenBank acession | AL121787 |
| Entrez gene record | 60468 |
| Pubmed identfication | 10949928 12829606 |
| RefSeq identity | NM_021813 |
| Classification | BTB domain containing Basic leucine zipper proteins |
| Havana BLAST/BLAT | OTTHUMG00000015216 |