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BACH2 Antibody, FITC Conjugated

BACH2 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, BACH2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBACH2
SpecificityThis is a highly specific antibody against BACH2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human BACH2
Gene ID number60468
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background BACH1 and BACH2, BACH1 and BACH2 have significant similarity to each other in BTB domain and Cap â, BACH1 appears ubiquitous, BACH2, BACH2 also plays an important role in the regulation of B cell development, BACH2 heterodimerizes with MAZR through its BTB/POZ domain to activate transcription, BACH2 is localized to the cytoplasm through its C-terminal cytoplasmic localization signal (CLS), In culture cells, MafF, Oxidative stressors aborted the CLS activity and induce nuclear accumulation of BACH2, They dimerize with other proteins and bind DNA to either represse or activate transcription depending on the dimer compositions, a 841 amino acid polypeptide, and MafG) are basic region leucine zipper (bZip) proteins that can function as transcriptional activators or repressors, are members of a novel family of BTB/POZ-basic region leucine zipper (bzip) factors, collar-type bZip domain but are otherwise divergent, heterodimerization partners of MafK, is an Nrf2-related transcription repressor and a tissue-specific partner of the Maf oncoprotein family, neuronal cells and is abundantly expressed in the early stages of B-cell differentiation, whereas BACH2 is restricted to monocytes, which mediates nucleocytoplasmic communciation to couple oxidative stress and transcription repression in mammalian cells, &euro, &euro, &tilde, &trade, Members of the small Maf family (MafK, nâ
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms BTBD25
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetBACH2 Conjugated
Short name FITC Conjugated, BACH2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, BACH2 (Antibody to)
Alternative techniqueantibodies
Identity 14078
Gene BACH2
Long gene name BTB domain and CNC homolog 2
Synonyms gene name BTB and CNC homology 1, basic leucine zipper transcription factor 2
Locus 6q15
Discovery year 2001-04-27
GenBank acession AL121787
Entrez gene record 60468
Pubmed identfication 10949928 12829606
RefSeq identity NM_021813
Classification BTB domain containing Basic leucine zipper proteins
Havana BLAST/BLAT OTTHUMG00000015216

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