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Bacillus anthracis lethal factor Antibody

Bacillus anthracis lethal factor Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBacillus anthracis lethal factor Antibody
Also known asBacillus anthracis lethal factor Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBacillus anthracis lethal factor
SpecificityThis is a highly specific antibody against Bacillus anthracis lethal factor
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from Bacillus anthracis lethal factor
Gene ID number1158731
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityOthers
Cross reactive species detailsAnthrax LF (Lethal Factor) produced by Bacillus anthracis
Background of the target antigen Cleavage invariably occurs within the N terminal proline rich region preceding the kinase domain, EF &, LF is not toxic by itself, LF then cleaves the N terminal of most dual specificity mitogen activated protein kinase kinases (MAPKKs or MAP2Ks) (except for MAP2K5), Once inside the cell, PA) composing the anthrax toxin produced by Bacillus anthracis, The proteasome may mediate a toxic process initiated by LF in the cell cytosol involving degradation of unidentified molecules that are essential for macrophage homeostasis, There may be other cytosolic targets of LF involved in cytotoxicity, This is an early step in LF intoxication, a bacteria which can infect many mammalian species and that may be fatal, but it is downstream of the cleavage by LF of MEK1 or other putative substrates, but when associated with Protective Antigen (PA), can then gain entry to cells, thus disrupting a sequence involved in directing specific protein protein interactions necessary for the assembly of signaling complexes, The protease enzyme Lethal Factor (LF) is one of the three proteins (LF
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Anthrax LF, Anthrax lethal toxin endopeptidase component, LEF_BACAN, LF, Lef, bacillus anthracis lethal factor, Anthrax lethal factor
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description Anthrax has a very high toxin level and is used in Biologic warfare, Aplha, Complex subunit associated factors are involved in hybridoma growth, Eosinohils, However 1 is a harmless product, NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation, Bacillus Anthracis and Cereus are the most known Bacilli
Gene targetBacillus anthracis lethal factor
Short nameBacillus anthracis lethal factor Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBacillus anthracis lethal factor (Antibody to)
Alternative techniqueantibodies

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