| Long name | Cy5, 5 Conjugated, BAD (Ser128) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | BAD Ser128 |
| Specificity | This phophorylation site is homologous to that of Ser129 in Rat, This is a highly specific antibody against BAD Ser128 |
| Modification | Phosphorylation |
| Modification site | Ser128 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 100-138/204 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from mouse BAD around the phosphorylation site of Ser128 |
| Gene ID number | 12015 |
| Swiss Prot | Q61337 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Rat, Mouse |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Appears to act as a link between growth factor receptor signaling and the apoptotic pathways, Bcl-2 and Bcl-W, Can reverse the death repressor activity of Bcl-X(L), Successfully competes for the binding to Bcl-X(L), but not that of Bcl-2, thereby affecting the level of heterodimerization of these proteins with BAX, Promotes cell death |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | BCL2L8 BBC2 |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | BAD (Ser128) Conjugated |
| Short name | Conjugated, BAD (Ser128) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, BCL2-associated a this GO nist on cell death (Ser128) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BAD and IDBG-53423 and ENSG00000002330 and 572, BBC2 and BCL2L8, BT, Bad and IDBG-137335 and ENSMUSG00000024959 and 12015, Cytoplasm, protein heterodimerization activity, this GO :0001666 and response to hypoxia and biological process this GO :0001836 and release of cytochrome c from mitochondria and biological process this GO :0005515 and protein binding and molecular function this GO :0005543 and phospholipid binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0006007 and glucose catabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0008283 and cell proliferation and biological process this GO :0008289 and lipid binding and molecular function this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0009725 and response to hormone and biological process this GO :0009749 and response to glucose and biological process this GO :0010033 and response to organic substance and biological process this GO :0010508 and positive regulation of autophagy and biological process this GO :0010918 and positive regulation of mitochondrial membrane potential and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0019050 and suppression by virus of host apoptotic process and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0030346 and protein phosphatase 2B binding and molecular function this GO :0032024 and positive regulation of insulin secretion and biological process this GO :0032355 and response to estradiol and biological process this GO :0032570 and response to progesterone and biological process this GO :0033133 and positive regulation of glucokinase activity and biological process this GO :0033574 and response to testosterone and biological process this GO :0034201 and response to oleic acid and biological process this GO :0035774 and positive regulation of insulin secretion involved in cellular response to glucose stimulus and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042493 and response to drug and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043200 and response to amino acid and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043422 and protein kinase B binding and molecular function this GO :0044342 and type B pancreatic cell proliferation and biological process this GO :0045087 and innate immune response and biological process this GO :0045471 and response to ethanol and biological process this GO :0045579 and positive regulation of B cell differentiation and biological process this GO :0045582 and positive regulation of T cell differentiation and biological process this GO :0045862 and positive regulation of proteolysis and biological process this GO :0046031 and ADP metabolic process and biological process this GO :0046034 and ATP metabolic process and biological process this GO :0046902 and regulation of mitochondrial membrane permeability and biological process this GO :0046931 and pore complex assembly and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0051592 and response to calcium ion and biological process this GO :0060139 and positive regulation of apoptotic process by virus and biological process this GO :0060154 and cellular process regulating host cell cycle in response to virus and biological process this GO :0071247 and cellular response to chromate and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071316 and cellular response to nicotine and biological process this GO :0071396 and cellular response to lipid and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0090200 and positive regulation of release of cytochrome c from mitochondria and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :0097192 and extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :0097202 and activation of cysteine-type endopeptidase activity and biological process this GO :1900740 and positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway and biological process this GO :1901216 and positive regulation of neuron death and biological process this GO :2000078 and positive regulation of type B pancreatic cell development and biological process this GO :2001244 and positive regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005543: phospholipid binding and also this GO :0008289: lipid binding and also this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process and also this GO :0019901: protein kinase binding and also this GO :0019903: protein phosphatase binding and also this GO :0030346: protein phosphatase 2B binding and also this GO :0043422: protein kinase B binding and also this GO :0046982: protein heterodimerization activity, this GO :0005543: phospholipid binding, this GO :0008289: lipid binding, this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0019901: protein kinase binding, this GO :0019903: protein phosphatase binding, this GO :0030346: protein phosphatase 2B binding, this GO :0043422: protein kinase B binding, this GO :0046982: protein heterodimerization activity, 55802 and IDBG-643918 and ENSBTAG00000012511 and 615013, BCL2-associated a this GO nist of cell death |
| Identity | 936 |
| Gene | BAD |
| Long gene name | BCL2 associated agonist of cell death |
| Locus | 11q13, 1 |
| Discovery year | 1997-10-16 |
| GenBank acession | AF021792 |
| Entrez gene record | 572 |
| Pubmed identfication | 8929532 |
| RefSeq identity | NM_032989 |
| Classification | BCL2 homology region 3 (BH3) only |
| Havana BLAST/BLAT | OTTHUMG00000134302 |
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