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Bad (Ser134) Antibody, ALEXA FLUOR 488

Bad (Ser134) Antibody, ALEXA FLUOR 488 size: 100ul 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 350
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Bad (Ser134) Polyclonal Antibody
Also known asAnti-Bad Ser134 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBad Ser134
SpecificityThis is a highly specific antibody against Bad Ser134
ModificationPhosphorylation
Modification SiteSer134
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human BAD around the phosphorylation site of Ser134
Gene ID Number572
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Alternative splicing of this gene results in two transcript variants which encode the same isoform, Bad is found on the outer mitochondrial membrane and, Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins, JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis, The latter interaction is critical for Bad phosphorylation at serine 155, The phosphorylation status of Bad represents a key checkpoint for death or cell survival, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival, once phosphorylated in response to growth stimuli, thus preventing them from binding with BAX, translocates to the cytoplasm, Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms BAD_HUMAN, BBC 2, BBC2, BBC6, BCL X / BCL 2 Binding Protein, BCL X Binding Protein, BCL2 antagonist of cell death protein, BCL2 associated agonist of cell death, BCL2 binding component 6, BCL2 binding protein, BCL2L8, Bad phospho Ser134, Bcl 2 Antagonist of Cell Death, Bcl 2 Binding Component 6, Bcl XL/Bcl 2 Associated Death Promoter, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl2 Associated Death Promoter, Bcl2 Like 8 Protein, Bcl2 antagonist of cell death, Bcl2-L-8, BclXL, Proapoptotic BH3 Only Protein, p-Bad S134, p-Bad phospho Ser134, Bad phospho S134, p- Bad Ser134
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Bad (Ser134) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetBad (Ser134)
Short nameBad (Ser134) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, BCL2-associated a this GO nist on cell death (Ser134) (Antibody to)
Alternative techniqueantibodies

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