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Bad (Ser134) Antibody, Cy3 Conjugated

Bad (Ser134) Antibody, Cy3 Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, Bad (Ser134) Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBad Ser134
SpecificityThis is a highly specific antibody against Bad Ser134
ModificationPhosphorylation
Modification siteSer134
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human BAD around the phosphorylation site of Ser134
Gene ID number572
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Alternative splicing of this gene results in two transcript variants which encode the same isoform, Bad is found on the outer mitochondrial membrane and, Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins, JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis, The latter interaction is critical for Bad phosphorylation at serine 155, The phosphorylation status of Bad represents a key checkpoint for death or cell survival, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival, once phosphorylated in response to growth stimuli, thus preventing them from binding with BAX, translocates to the cytoplasm, Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms BAD_HUMAN, BBC 2, BBC2, BBC6, BCL X / BCL 2 Binding Protein, BCL X Binding Protein, BCL2 antagonist of cell death protein, BCL2 associated agonist of cell death, BCL2 binding component 6, BCL2 binding protein, BCL2L8, Bad phospho Ser134, Bcl 2 Antagonist of Cell Death, Bcl 2 Binding Component 6, Bcl XL/Bcl 2 Associated Death Promoter, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl2 Associated Death Promoter, Bcl2 Like 8 Protein, Bcl2 antagonist of cell death, Bcl2-L-8, BclXL, Proapoptotic BH3 Only Protein, p-Bad S134, p-Bad phospho Ser134, Bad phospho S134, p- Bad Ser134
Properties 1 of the Bad (Ser134) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetBad (Ser134) Conjugated
Short name Conjugated, Bad (Ser134) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, BCL2-associated a this GO nist on cell death (Ser134) (Antibody to)
Alternative techniqueantibodies

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