Name : BAG5 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2584091356
| Long name | BAG5 Primary Polyclonal Antibody |
| Also known as | BAG5 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | BAG5 |
| Specificity | This is a highly specific antibody against BAG5 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BAG5 |
| Gene ID number | 9529 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | A BAG domain near the C terminus, BAG1 is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL 2, BAG5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAGheterodimerization, It has been hypothesized that the BAG5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, It is believed that BAG5 will play an important role in the mechanisms of neuronal death, Raf protein kinase, growth factor receptors and members of the heat shock protein 70 kDa family, may bind and inhibit the chaperone activity of Hsc70/Hsp70, steroid hormone receptors, which will cause increased protein aggregation and cell death by disinhibition of hsp70â, &euro, &trade, BAG5 is a member of the BAG1 related protein family, s anti apoptotic function |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | BAG 5, BAG-5, BAG5_HUMAN, BCL2 associated athanogene 5, KIAA0873, BAG family molecular chaperone regulator 5 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | BAG5 |
| Short name | BAG5 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | B-cell CLL/lymphoma 2-associated athanogene 5 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BAG-5, BAG5 and IDBG-21751 and ENSG00000166170 and 9529, BAG5 and IDBG-635463 and ENSBTAG00000017361 and 522854, Bag5 and IDBG-173485 and ENSMUSG00000049792 and 70369, chaperone binding, nuclei, this GO :0005634 and nucleus and cellular component this GO :0006457 and protein folding and biological process this GO :0016020 and membrane and cellular component this GO :0016234 and inclusion body and cellular component this GO :0031397 and negative regulation of protein ubiquitination and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051087 and chaperone binding and molecular function this GO :0051444 and negative regulation of ubiquitin-protein transferase activity and biological process this GO :0061084 and negative regulation of protein refolding and biological process this GO :0070997 and neuron death and biological process this GO :0090083 and regulation of inclusion body assembly and biological process, this GO :0031625: ubiquitin protein ligase binding, this GO :0031625: ubiquitin protein ligase binding and also this GO :0051087: chaperone binding, this GO :0051087: chaperone binding, BCL2-associated athanogene 5 |
| Identity | 941 |
| Gene | BAG5 |
| Long gene name | BCL2 associated athanogene 5 |
| Locus | 14q32, 33 |
| Discovery year | 1999-04-23 |
| GenBank acession | AF095195 |
| Entrez gene record | 9529 |
| Pubmed identfication | 9873016 15603737 |
| Classification | BCL2 associated athanogene family |
| Havana BLAST/BLAT | OTTHUMG00000171763 |