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BAG5 Antibody, FITC Conjugated

BAG5 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, BAG5 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBAG5
SpecificityThis is a highly specific antibody against BAG5
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human BAG5
Gene ID number9529
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A BAG domain near the C terminus, BAG1 is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL 2, BAG5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAGheterodimerization, It has been hypothesized that the BAG5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, It is believed that BAG5 will play an important role in the mechanisms of neuronal death, Raf protein kinase, growth factor receptors and members of the heat shock protein 70 kDa family, may bind and inhibit the chaperone activity of Hsc70/Hsp70, steroid hormone receptors, which will cause increased protein aggregation and cell death by disinhibition of hsp70â, &euro, &trade, BAG5 is a member of the BAG1 related protein family, s anti apoptotic function
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetBAG5 Conjugated
Short name FITC Conjugated, BAG5 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, B-cell CLL/lymphoma 2-associated athanogene 5 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BAG-5, BAG5 and IDBG-21751 and ENSG00000166170 and 9529, BAG5 and IDBG-635463 and ENSBTAG00000017361 and 522854, Bag5 and IDBG-173485 and ENSMUSG00000049792 and 70369, chaperone binding, nuclei, this GO :0005634 and nucleus and cellular component this GO :0006457 and protein folding and biological process this GO :0016020 and membrane and cellular component this GO :0016234 and inclusion body and cellular component this GO :0031397 and negative regulation of protein ubiquitination and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051087 and chaperone binding and molecular function this GO :0051444 and negative regulation of ubiquitin-protein transferase activity and biological process this GO :0061084 and negative regulation of protein refolding and biological process this GO :0070997 and neuron death and biological process this GO :0090083 and regulation of inclusion body assembly and biological process, this GO :0031625: ubiquitin protein ligase binding, this GO :0031625: ubiquitin protein ligase binding and also this GO :0051087: chaperone binding, this GO :0051087: chaperone binding, BCL2-associated athanogene 5
Identity 941
Gene BAG5
Long gene name BCL2 associated athanogene 5
Locus 14q32, 33
Discovery year 1999-04-23
GenBank acession AF095195
Entrez gene record 9529
Pubmed identfication 9873016 15603737
Classification BCL2 associated athanogene family
Havana BLAST/BLAT OTTHUMG00000171763

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