BAG6 Antibody

BAG6 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	BAG6 Primary Polyclonal Antibody
Also known as	BAG6 PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	BAG6
Specificity	This is a highly specific antibody against BAG6
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BAT3/BAG6
Tested Applications	IF(IHC-P), IHC-P, WB
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Acts in part by regulating stability of proteins and their degradation by the proteasome, Also required during spermatogenesis for synaptonemal complex assembly via its interaction with HSPA2, BAG6/BAT3 acts by facilitating TA membrane proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, In this context, Key component of the BAG6/BAT3 complex, Participates in endoplasmic reticulum stress-induced apoptosis via its interaction with AIFM1/AIF by regulating AIFM1/AIF stability and preventing its degradation, Required for selective ubiquitin-mediated degradation of defective nascent chain polypeptides by the proteasome, TA membrane proteins, a cytosolic multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane, also named type II transmembrane proteins, by inhibiting polyubiquitination and subsequent proteasomal degradation of HSPA2, contain a single C-terminal transmembrane region, insertion of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane and regulation of chromatin, interacts with the transmembrane region of newly released TA proteins and transfers them to ASNA1/TRC40 for targeting to the endoplasmic reticulum membrane, may play a role in immuno-proteasomes to generate antigenic peptides via targeted degradation, thereby playing a role in antigen presentation in immune response, Chaperone that plays a key role in various processes such as apoptosis
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	BAG-6, BAG6, BAG6_HUMAN, BCL2-associated athanogene 6, Bag6, D6S52E, G3, HLA B associated transcript 3, HLA-B-associated transcript 3, Large proline-rich protein BAG6, Protein G3, Protein Scythe, family molecular chaperone regulator 6
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	BAG6
Short name	BAG6 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	B-cell CLL/lymphoma 2-associated athanogene 6 (Antibody to)
Alternative technique	antibodies
Alternative to gene target	BAG-6 and BAT3 and D6S52E and G3, BAG6 and IDBG-125033 and ENSG00000204463 and 7917, BT, Bag6 and IDBG-176819 and ENSMUSG00000024392 and 224727, nuclei, proteasome binding, this GO :0001822 and kidney development and biological process this GO :0002376 and immune system process and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0006810 and transport and biological process this GO :0007130 and synaptonemal complex assembly and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007420 and brain development and biological process this GO :0009790 and embryo development and biological process this GO :0016568 and chromatin modification and biological process this GO :0018393 and internal peptidyl-lysine acetylation and biological process this GO :0030154 and cell differentiation and biological process this GO :0030324 and lung development and biological process this GO :0030544 and Hsp70 protein binding and molecular function this GO :0031593 and polyubiquitin binding and molecular function this GO :0032435 and negative regulation of proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0043022 and ribosome binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0050821 and protein stabilization and biological process this GO :0070059 and intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and biological process this GO :0070628 and proteasome binding and molecular function this GO :0071816 and tail-anchored membrane protein insertion into ER membrane and biological process this GO :0071818 and BAT3 complex and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0030544: Hsp70 protein binding and also this GO :0031593: polyubiquitin binding and also this GO :0043022: ribosome binding and also this GO :0070628: proteasome binding, this GO :0030544: Hsp70 protein binding, this GO :0031593: polyubiquitin binding, this GO :0043022: ribosome binding, this GO :0070628: proteasome binding, 23547 and IDBG-634053 and ENSBTAG00000019685 and 508605, BCL2-associated athanogene 6
Identity	13919
Gene	BAG6
Long gene name	BCL2 associated athanogene 6
Synonyms gene	BAT3
Synonyms gene name	HLA-B associated transcript 3
Synonyms	G3 D6S52E
Locus	6p21, 33
Discovery year	2001-07-13
GenBank acession	M31294
Entrez gene record	7917
Pubmed identfication	2156268
RefSeq identity	NM_080703
Classification	BCL2 associated athanogene family
Havana BLAST/BLAT	OTTHUMG00000031171

BAG6 Antibody

BAG6 Antibody size: 0.1ml 263

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