Name : BBS10 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7351088209
| Long name | BBS10 Primary Polyclonal Antibody |
| Also known as | BBS10 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | BBS10 |
| Specificity | This is a highly specific antibody against BBS10 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BBS10 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | BBS genes map to multiple loci and encode fourteen proteins, BBS1-BBS14, BBS10 (Bardet-Biedl syndrome 10), BBS10 localizes to the basal body of primary cilium and assists in protein folding upon ATP hydrolysis, C12orf58 or FLJ23560, Inhibition of BBS10 has been found to impair ciliogenesis, Many BBS genes encode basal body or cilia proteins, Other associated clinical findings in BBS patients include diabetes, The gene encoding BBS10 contains two exons and maps to human chromosome 12q21, activate the glycogen synthase kinase 3 pathway and cause peroxisome proliferator-activated receptor nuclear accumulation, also known as chromosome 12 open reading fame 58, and congenital heart defects, and developmental delay, hypertension, hypogenitalism, is a novel 723 amino acid protein belonging to the TCP-1 chaperonin family, photoreceptor degeneration, polydactyly, renal abnormalities, suggesting that BBS is a ciliary dysfunction disorder, 2, Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | BBS10_HUMAN, Bardet Biedl syndrome 10 protein homolog, C12orf58, FLJ23560, RGD1560748, Bardet Biedl syndrome 10 protein |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | BBS10 |
| Short name | BBS10 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | BBS10 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 26291 |
| Gene | BBS10 |
| Long gene name | Bardet-Biedl syndrome 10 |
| Synonyms gene | C12orf58 |
| Synonyms gene name | chromosome 12 open reading frame 58 |
| Synonyms | FLJ23560 |
| Locus | 12q21, 2 |
| Discovery year | 2006-02-09 |
| GenBank acession | BC026355 |
| Entrez gene record | 79738 |
| Pubmed identfication | 16582908 |
| RefSeq identity | NM_024685 |
| Classification | Bardet-Biedl syndrome associated Chaperonins |
| Havana BLAST/BLAT | OTTHUMG00000147352 |