Name : BBS10 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN7492242152
| Long name | ALEXA FLUOR 488 Conjugated, BBS10 Polyclonal Antibody |
| Also known as | Anti-BBS10 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | BBS10 |
| Specificity | This is a highly specific antibody against BBS10 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BBS10 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | BBS genes map to multiple loci and encode fourteen proteins, BBS1-BBS14, BBS10 (Bardet-Biedl syndrome 10), BBS10 localizes to the basal body of primary cilium and assists in protein folding upon ATP hydrolysis, C12orf58 or FLJ23560, Inhibition of BBS10 has been found to impair ciliogenesis, Many BBS genes encode basal body or cilia proteins, Other associated clinical findings in BBS patients include diabetes, The gene encoding BBS10 contains two exons and maps to human chromosome 12q21, activate the glycogen synthase kinase 3 pathway and cause peroxisome proliferator-activated receptor nuclear accumulation, also known as chromosome 12 open reading fame 58, and congenital heart defects, and developmental delay, hypertension, hypogenitalism, is a novel 723 amino acid protein belonging to the TCP-1 chaperonin family, photoreceptor degeneration, polydactyly, renal abnormalities, suggesting that BBS is a ciliary dysfunction disorder, 2, Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | FLJ23560 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the BBS10 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | BBS10 |
| Short name | BBS10 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, BBS10 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 26291 |
| Gene | BBS10 |
| Long gene name | Bardet-Biedl syndrome 10 |
| Synonyms gene | C12orf58 |
| Synonyms gene name | chromosome 12 open reading frame 58 |
| Locus | 12q21, 2 |
| Discovery year | 2006-02-09 |
| GenBank acession | BC026355 |
| Entrez gene record | 79738 |
| Pubmed identfication | 16582908 |
| RefSeq identity | NM_024685 |
| Classification | Bardet-Biedl syndrome associated Chaperonins |
| Havana BLAST/BLAT | OTTHUMG00000147352 |