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BBS10 Antibody, FITC Conjugated

BBS10 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, BBS10 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBBS10
SpecificityThis is a highly specific antibody against BBS10
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human BBS10
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background BBS genes map to multiple loci and encode fourteen proteins, BBS1-BBS14, BBS10 (Bardet-Biedl syndrome 10), BBS10 localizes to the basal body of primary cilium and assists in protein folding upon ATP hydrolysis, C12orf58 or FLJ23560, Inhibition of BBS10 has been found to impair ciliogenesis, Many BBS genes encode basal body or cilia proteins, Other associated clinical findings in BBS patients include diabetes, The gene encoding BBS10 contains two exons and maps to human chromosome 12q21, activate the glycogen synthase kinase 3 pathway and cause peroxisome proliferator-activated receptor nuclear accumulation, also known as chromosome 12 open reading fame 58, and congenital heart defects, and developmental delay, hypertension, hypogenitalism, is a novel 723 amino acid protein belonging to the TCP-1 chaperonin family, photoreceptor degeneration, polydactyly, renal abnormalities, suggesting that BBS is a ciliary dysfunction disorder, 2, Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms FLJ23560
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetBBS10 Conjugated
Short name FITC Conjugated, BBS10 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, BBS10 (Antibody to)
Alternative techniqueantibodies
Identity 26291
Gene BBS10
Long gene name Bardet-Biedl syndrome 10
Synonyms gene C12orf58
Synonyms gene name chromosome 12 open reading frame 58
Locus 12q21, 2
Discovery year 2006-02-09
GenBank acession BC026355
Entrez gene record 79738
Pubmed identfication 16582908
RefSeq identity NM_024685
Classification Bardet-Biedl syndrome associated Chaperonins
Havana BLAST/BLAT OTTHUMG00000147352

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