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BBS5 Antibody

BBS5 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBBS5 Primary Polyclonal Antibody
Also known asBBS5 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBBS5
SpecificityThis is a highly specific antibody against BBS5
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range220-270/341
Subcellular location Cell membrane, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BBS5
Gene ID number129880
Swiss ProtQ8N3I7
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane, Required for BBSome complex ciliary localization but not for the proper complex assembly, The BBSome complex, The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function, This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane, together with the LTZL1, which localizes to the basal body and contacts the BBSome, The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BBS5, Bardet-Biedl syndrome 5 protein
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetBBS5
Short nameBBS5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBBS5 (Antibody to)
Alternative techniqueantibodies
Identity 970
Gene BBS5
Long gene name Bardet-Biedl syndrome 5
Synonyms DKFZp762I194
Locus 2q31, 1
Discovery year 1998-03-25
GenBank acession AY604003
Entrez gene record 129880
Pubmed identfication 9888993 10053027
RefSeq identity NM_152384
Classification Bardet-Biedl syndrome associated BBSome
Havana BLAST/BLAT OTTHUMG00000132207

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