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BCL-2 (1A5) Antibody, Biotin Conjugated

BCL-2 (1A5) Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, BCL-2 (1A5) Monoclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBCL-2
SpecificityThis is a highly specific antibody against BCL-2
ModificationUnmodified
Modification siteNone
ClonalityMonoclonal
Clone1A5
Concentration1ug per 1ul
SourceRecombinant protein fragment (1-220 amino acids range) of human Bcl-2
Gene ID number596
Swiss ProtP10415
Tested applicationsWB
Recommended dilutionsWB(1:100-1000)
Crossreactivity Mouse, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Appears to function in a feedback loop system with caspases, Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1), May attenuate inflammation by impairing NLRP1-inflammasome activation, Regulates cell death by controlling the mitochondrial membrane permeability, hence CASP1 activation and IL1B release, Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells
Purification methodPurified by Protein G
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms Bcl-2 PPP1R50
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetBCL-2 (1A5) Conjugated
Short name Conjugated, BCL-2 (1A5) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, BCL-2 (1A5) (Antibody to)
Alternative techniqueantibodies
Identity 990
Gene BCL2
Long gene name BCL2, apoptosis regulator
Synonyms gene name B-cell CLL/lymphoma 2
Synonyms name protein phosphatase 1, regulatory subunit 50
Locus 18q21, 33
Discovery year 2001-06-22
GenBank acession M14745
Entrez gene record 596
RefSeq identity NM_000633 NM_000657
Classification Protein phosphatase 1 regulatory subunits BCL2 family
Havana BLAST/BLAT OTTHUMG00000132791
Locus Specific Databases LRG_1113

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