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BCL-2 (1A5) Monoclonal Antibody

BCL-2 (1A5) Monoclonal Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBCL-2 (1A5) Monoclonal Antibody
Also known asBCL-2 (1A5) Monoclonal Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBCL-2
SpecificityThis is a highly specific antibody against BCL-2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number1A5
Concentration1ug per 1ul
SourceRecombinant protein fragment (1-220 amino acids range) of human Bcl-2
Gene ID number596
Swiss ProtP10415
Tested ApplicationsWB
Recommended dilutionsWB(1:100-1000)
Cross reactivity Mouse, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Appears to function in a feedback loop system with caspases, Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1), May attenuate inflammation by impairing NLRP1-inflammasome activation, Regulates cell death by controlling the mitochondrial membrane permeability, hence CASP1 activation and IL1B release, Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells
Purification methodPurified by Protein G
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BCL2, Apoptosis regulator Bcl-2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetBCL-2 (1A5) Monoclonal
Short nameBCL-2 (1A5) Monoclonal Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative nameBCL-2 (1A5) monoclonal (Antibody to)
Alternative techniqueantibodies
Identity 990
Gene BCL2
Long gene name BCL2, apoptosis regulator
Synonyms gene name B-cell CLL/lymphoma 2
Synonyms Bcl-2 PPP1R50
Synonyms name protein phosphatase 1, regulatory subunit 50
Locus 18q21, 33
Discovery year 2001-06-22
GenBank acession M14745
Entrez gene record 596
RefSeq identity NM_000633 NM_000657
Classification Protein phosphatase 1 regulatory subunits BCL2 family
Havana BLAST/BLAT OTTHUMG00000132791
Locus Specific Databases LRG_1113

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