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Bcl-2(Thr129) Antibody, ALEXA FLUOR 488

Bcl-2(Thr129) Antibody, ALEXA FLUOR 488 size: 100ul 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 350
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Bcl-2(Thr129) Polyclonal Antibody
Also known asAnti-Bcl-2Thr129 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBcl-2Thr129
SpecificityThis is a highly specific antibody against Bcl-2Thr129
ModificationPhosphorylation
Modification SiteThr129
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from rat Bcl-2 around the phosphorylation site of Thr129
Gene ID Number24224
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen BAD, BAK and BclX(L), BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1), BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells, Constitutive expression of BCL2, Heterodimerization with BAX requires intact BH1 and BH2 domains, It appears to function in a feedback loop system with caspases, It can form homodimers, It regulates cell death by controlling the mitochondrial membrane permeability, Two transcript variants (alpha and beta) produced by alternate splicing, and heterodimers with BAX, and is necessary for anti-apoptotic activity, differ in their C-terminal ends, is thought to be the cause of follicular lymphoma, such as in the case of translocation of BCL2 to Ig heavy chain locus, BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms 2, AW986256, Apoptosis regulator Bcl 2, Apoptosis regulator Bcl2, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, B cell lymphoma 2, B-cell, BCL2 protein, BCL2_HUMAN, Bcl 2, Bcl-2, Bcl-2 phospho Thr129, Bcl2, C430015F12Rik, D630044D05Rik, D830018M01Rik, Leukemia/lymphoma, Oncogene B-cell leukemia 2, p-Bcl-2 Thr129, Bcl-2 phospho T129
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Bcl-2(Thr129) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetBcl-2(Thr129)
Short nameBcl-2(Thr129) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Bcl-2(Thr129) (Antibody to)
Alternative techniqueantibodies

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