Bcl-2 (Thr56) Antibody, Biotin Conjugated

Bcl-2 (Thr56) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 350

Size 0.1ml

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Long name	Biotin Conjugated, Bcl-2 (Thr56) Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	Bcl-2 Thr56
Specificity	This is a highly specific antibody against Bcl-2 Thr56
Modification	Phosphorylation
Modification site	Thr56
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic phosphopeptide derived from human Bcl-2 around the phosphorylation site of Thr56
Gene ID number	596
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Also interacts with APAF1, BAD, BAK and BclX(L), BBC3, BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1), BCL2L1 and BNIPL, Constitutive expression of BCL2, Heterodimerization with BAX requires intact BH1 and BH2 domains, It appears to function in a feedback loop system with caspases, It can form homodimers, It regulates cell death by controlling the mitochondrial membrane permeability, RAF1, TP53BP2, Two transcript variants (alpha and beta) produced by alternate splicing, and heterodimers with BAX, and is necessary for anti-apoptotic activity, differ in their C-terminal ends, is thought to be the cause of follicular lymphoma, such as in the case of translocation of BCL2 to Ig heavy chain locus, BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes, BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	2, AW986256, Apoptosis regulator Bcl 2, Apoptosis regulator Bcl2, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, B cell lymphoma 2, B-cell, BCL2 protein, BCL2_HUMAN, Bcl 2, Bcl-2, Bcl2, Bcl2 phospho Thr56, C430015F12Rik, D630044D05Rik, D830018M01Rik, Leukemia/lymphoma, Oncogene B-cell leukemia 2, p-Bcl2 phospho T56, Bcl2 phospho T56
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	Bcl-2 (Thr56) Conjugated
Short name	Conjugated, Bcl-2 (Thr56) Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, Bcl-2 (Thr56) (Antibody to)
Alternative technique	antibodies

Bcl-2 (Thr56) Antibody, Biotin Conjugated

Bcl-2 (Thr56) Antibody, Biotin Conjugated size: 0.1ml 350

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