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Bcl-xL (Thr115) Antibody, Biotin Conjugated

Bcl-xL (Thr115) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, Bcl-xL (Thr115) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBcl-xL Thr115
SpecificityThis is a highly specific antibody against Bcl-xL Thr115
ModificationPhosphorylation
Modification siteThr115
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range95-140/233
Subcellular location Mitochondrion, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human BCL2L1 around the phosphorylation site of Thr115
Gene ID number598
Swiss ProtQ07817
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis, Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, During synaptic stimulation, Inhibits activation of caspases, Isoform Bcl-X(L) also regulates presynaptic plasticity, Isoform Bcl-X(S) promotes apoptosis, from the mitochondrial membrane, including neurotransmitter release and recovery, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F(0) activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles, number of axonal mitochondria as well as size and number of synaptic vesicle clusters, Potent inhibitor of cell death
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms Apoptosis regulator Bcl-X, BCL-XL/S, BCL2L, BCL2L1, BCLXL, BCLXS, Bcl-2-like protein 1, Bcl-X, Bcl2-L-1, PPP1R52, bcl-xL, bcl-xS, BCLX
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetBcl-xL (Thr115) Conjugated
Short name Conjugated, Bcl-xL (Thr115) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Bcl-xL (Thr115) (Antibody to)
Alternative techniqueantibodies

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