| Long name | 1, 2, 2) Monoclonal Antibody, BCL10 (1185CT13 |
| Also known as | 1, 2, 2) Monoclonal Antibody, BCL10 (1185CT13 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | BCL10 |
| Specificity | This is a highly specific antibody against BCL10 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 1, 1185CT13, 2, 2 |
| Source | This BCL10 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-143 amino acids from the human region of human BCL10 |
| Gene ID number | 8915 |
| Swiss Prot | O95999 |
| Tested Applications | FCM, IHC-P, WB |
| Recommended dilutions | FC(1:25), IHC-P(1:25), WB(1:1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Is a substrate for MALT1 (PubMed:18264101), May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex, Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK, Involved in adaptive immune response (PubMed:25365219) |
| Purification method | This antibody is purified through a protein G column, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | B-cell CLL/lymphoma 10, B-cell lymphoma/leukemia 10, BCL10, Bcl-10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, CARMEN, CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER, Cellular homolog of vCARMEN, Cellular-E10, IMD37, Mammalian CARD-containing adapter molecule E10, c-E10, cCARMEN, hCLAP, mE10, CLAP |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 1, 2, 2) Monoclonal, BCL10 (1185CT13 |
| Short name | 1, 2, 2) Monoclonal Antibody, BCL10 (1185CT13 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 1, 2, 2) monoclonal (Antibody to), B-cellular CLL/lymphoma 10 (1185CT13 |
| Alternative technique | antibodies |
| Alternative to gene target | BCL10 and IDBG-100044 and ENSG00000142867 and 8915, BCL10 and IDBG-637289 and ENSBTAG00000013851 and 540824, Bcl10 and IDBG-198751 and ENSMUSG00000028191 and 12042, DNA-templated and biological process this GO :0046696 and lipopolysaccharide receptor complex and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050856 and regulation of T cell receptor signaling pathway and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0051059 and NF-kappaB binding and molecular function this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051259 and protein oli this GO merization and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0070231 and T cell apoptotic process and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process, NF-kappaB binding, c-E10 and CARMEN and CIPER and CLAP and mE10, nuclei, this GO :0001772 and immunological synapse and cellular component this GO :0001783 and B cell apoptotic process and biological process this GO :0001843 and neural tube closure and biological process this GO :0002020 and protease binding and molecular function this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002237 and response to molecule of bacterial origin and biological process this GO :0002250 and adaptive immune response and biological process this GO :0002906 and negative regulation of mature B cell apoptotic process and biological process this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005881 and cytoplasmic microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006968 and cellular defense response and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008134 and transcription factor binding and molecular function this GO :0008219 and cell death and biological process this GO :0009620 and response to fungus and biological process this GO :0016064 and immunoglobulin mediated immune response and biological process this GO :0019209 and kinase activator activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0019900 and kinase binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032094 and response to food and biological process this GO :0032449 and CBM complex and cellular component this GO :0032765 and positive regulation of mast cell cytokine production and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042101 and T cell receptor complex and cellular component this GO :0042109 and lymphotoxin A biosynthetic process and biological process this GO :0042226 and interleukin-6 biosynthetic process and biological process this GO :0042327 and positive regulation of phosphorylation and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043130 and ubiquitin binding and molecular function this GO :0043234 and protein complex and cellular component this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043422 and protein kinase B binding and molecular function this GO :0043621 and protein self-association and molecular function this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045416 and positive regulation of interleukin-8 biosynthetic process and biological process this GO :0045893 and positive regulation of transcription, this GO :0002020: protease binding, this GO :0002020: protease binding and also this GO :0003713: transcription coactivator activity and also this GO :0005515: protein binding and also this GO :0008022: protein C-terminus binding and also this GO :0008134: transcription factor binding and also this GO :0019209: kinase activator activity and also this GO :0019899: enzyme binding and also this GO :0019900: kinase binding and also this GO :0019901: protein kinase binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0043130: ubiquitin binding and also this GO :0043422: protein kinase B binding and also this GO :0043621: protein self-association and also this GO :0051059: NF-kappaB binding, this GO :0003713: transcription coactivator activity, this GO :0005515: protein binding, this GO :0008022: protein C-terminus binding, this GO :0008134: transcription factor binding, this GO :0019209: kinase activator activity, this GO :0019899: enzyme binding, this GO :0019900: kinase binding, this GO :0019901: protein kinase binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0043130: ubiquitin binding, this GO :0043422: protein kinase B binding, this GO :0043621: protein self-association, this GO :0051059: NF-kappaB binding, B-cell CLL/lymphoma 10 |
| Identity | 989 |
| Gene | BCL10 |
| Long gene name | B-cell CLL/lymphoma 10 |
| Synonyms | CARMEN CIPER mE10 c-E10 CLAP |
| Synonyms name | CARD-like apoptotic protein CARD-containing apoptotic signaling protein CARD containing molecule enhancing NF-kB caspase-recruiting domain-containing protein CARD-containing proapoptotic protein |
| Locus | 1p22, 3 |
| Discovery year | 1999-01-08 |
| GenBank acession | AJ006288 |
| Entrez gene record | 8915 |
| Pubmed identfication | 9989495 |
| RefSeq identity | NM_003921 |
| Classification | Caspase recruitment domain containing |
| Havana BLAST/BLAT | OTTHUMG00000009965 |
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