| Also known as | BCL10 |
| Other names | B-cell CLL/lymphoma 10, B-cell CLL/lymphoma 10, B-cell lymphoma/leukemia 10, B-cell lymphoma/leukemia 10, Bcl-10, CARD containing molecule enhancing NF-kB, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CED-3/ICH-1 prodomain homologous E10-like regulator, CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER, Cellular homolog of vCARMEN, Cellular-E10, Mammalian CARD-containing adapter molecule E10, c-E10, cCARMEN, cCARMEN, caspase-recruiting domain-containing protein, cellular homolog of vCARMEN, cellular-E10, hCLAP, hCLAP, mE10, mammalian CARD-containing adapter molecule E10, B-cell lymphoma/leukemia 10 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | BCL10 |
| Gene name synonims | N/A |
| Other gene names | BCL10, Bcl-10, CARMEN, CIPER, CIPER, CIPER, CLAP, CLAP, c-E10, c-E10, cCARMEN, hCLAP, mE10, mE10, BCL10 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | kappa, IgG1 |
| Clone | BL10/411 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Expression of BCL10 was shown to induce NFkappaB activation in a NIK-dependent pathway, In MALT lymphomas with the t(1, It was identified through its direct involvement in t(1, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas, This particular antibody might cross react with speacies outside of the listed ones, although at a much lower level, is found in a number of apoptotic regulatory molecules, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, with an N-terminal caspase recruitment domain (CARD), 14) of mucosa-associated lymphoid tissue (MALT) lymphoma, 14) translocation, BCL10 |
| Purification method | N/A |
| Form/Appearance | N/A |
| Concentration | N/A |
| Storage and shipping | Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications: | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA) |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target | BCL10 |
| Short name | BCL10 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | B-cellular CLL/lymphoma 10 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BCL10 and IDBG-100044 and ENSG00000142867 and 8915, BCL10 and IDBG-637289 and ENSBTAG00000013851 and 540824, Bcl10 and IDBG-198751 and ENSMUSG00000028191 and 12042, DNA-templated and biological process this GO :0046696 and lipopolysaccharide receptor complex and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050856 and regulation of T cell receptor signaling pathway and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0051059 and NF-kappaB binding and molecular function this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051259 and protein oli this GO merization and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0070231 and T cell apoptotic process and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process, NF-kappaB binding, c-E10 and CARMEN and CIPER and CLAP and mE10, nuclei, this GO :0001772 and immunological synapse and cellular component this GO :0001783 and B cell apoptotic process and biological process this GO :0001843 and neural tube closure and biological process this GO :0002020 and protease binding and molecular function this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002237 and response to molecule of bacterial origin and biological process this GO :0002250 and adaptive immune response and biological process this GO :0002906 and negative regulation of mature B cell apoptotic process and biological process this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005881 and cytoplasmic microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006968 and cellular defense response and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008134 and transcription factor binding and molecular function this GO :0008219 and cell death and biological process this GO :0009620 and response to fungus and biological process this GO :0016064 and immunoglobulin mediated immune response and biological process this GO :0019209 and kinase activator activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0019900 and kinase binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032094 and response to food and biological process this GO :0032449 and CBM complex and cellular component this GO :0032765 and positive regulation of mast cell cytokine production and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042101 and T cell receptor complex and cellular component this GO :0042109 and lymphotoxin A biosynthetic process and biological process this GO :0042226 and interleukin-6 biosynthetic process and biological process this GO :0042327 and positive regulation of phosphorylation and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043130 and ubiquitin binding and molecular function this GO :0043234 and protein complex and cellular component this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043422 and protein kinase B binding and molecular function this GO :0043621 and protein self-association and molecular function this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045416 and positive regulation of interleukin-8 biosynthetic process and biological process this GO :0045893 and positive regulation of transcription, this GO :0002020: protease binding, this GO :0002020: protease binding and also this GO :0003713: transcription coactivator activity and also this GO :0005515: protein binding and also this GO :0008022: protein C-terminus binding and also this GO :0008134: transcription factor binding and also this GO :0019209: kinase activator activity and also this GO :0019899: enzyme binding and also this GO :0019900: kinase binding and also this GO :0019901: protein kinase binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0043130: ubiquitin binding and also this GO :0043422: protein kinase B binding and also this GO :0043621: protein self-association and also this GO :0051059: NF-kappaB binding, this GO :0003713: transcription coactivator activity, this GO :0005515: protein binding, this GO :0008022: protein C-terminus binding, this GO :0008134: transcription factor binding, this GO :0019209: kinase activator activity, this GO :0019899: enzyme binding, this GO :0019900: kinase binding, this GO :0019901: protein kinase binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0043130: ubiquitin binding, this GO :0043422: protein kinase B binding, this GO :0043621: protein self-association, this GO :0051059: NF-kappaB binding, B-cell CLL/lymphoma 10 |
| Identity | 989 |
| Gene | BCL10 |
| Long gene name | B-cell CLL/lymphoma 10 |
| Synonyms | CARMEN CIPER mE10 c-E10 CLAP |
| Synonyms name | CARD-like apoptotic protein CARD-containing apoptotic signaling protein CARD containing molecule enhancing NF-kB caspase-recruiting domain-containing protein CARD-containing proapoptotic protein |
| Locus | 1p22, 3 |
| Discovery year | 1999-01-08 |
| GenBank acession | AJ006288 |
| Entrez gene record | 8915 |
| Pubmed identfication | 9989495 |
| RefSeq identity | NM_003921 |
| Classification | Caspase recruitment domain containing |
| Havana BLAST/BLAT | OTTHUMG00000009965 |
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