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Bcl2 modifying factor Antibody, Biotin Conjugated

Bcl2 modifying factor Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, Bcl2 modifying factor Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBcl2 modying factor
SpecificityThis is a highly specific antibody against Bcl2 modying factor
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Bcl2 modifying factor
Gene ID number90427
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background BID, Bad, Bcl-2 modifying factor (Bmf) is a BH3-only protein that binds prosurvival Bcl-2 family members to initiate apoptosis, Bik, Bim, Binding results in a caspase cascade leading to apoptosis, Bmf is sequestered to Myosin V motors on Actin in the cytoskeleton by associating with Dynein light chain 2 (DLC2) homodimers, Bmf is widely expressed in tissues such as pancreas, Bmf then translocates to the mitochondria, Hrk, If the cell undergoes loss of attachment (anoikis), NOXA, PUMA and Bmf, The BH3 domain of Bmf facilitates binding to a hydrophobic groove on the surface of Bcl-2, The gene encoding Bmf maps to chromosome 15q14, and in hematopoietic tissues, are proapoptotic members of the Bcl-2 family, liver and kidney, the cytoskeleton is disrupted and Bmf is released from DLC2, where Bcl-2 (an anti-apoptotic family member) is sequestered, which include Blk, The BH3-only proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms BMF_HUMAN, Bcl-2-modying factor, Bcl2 modying factor, Bmf, FLJ00065, Bcl 2 modying factor
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Description Complex subunit associated factors are involved in hybridoma growth, Eosinohils, NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation, Aplha
Gene targetBcl2 modifying factor Conjugated
Short name Conjugated, Bcl2 modifying factor Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, B-cell CLL/lymphoma 2 modifying factor (Antibody to)
Alternative techniqueantibodies

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