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Bcl2 (Ser87) Antibody

Bcl2 (Ser87) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBcl2 (Ser87) Primary Polyclonal Antibody
Also known asBcl2 (Ser87) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBcl2 Ser87
SpecificityThis is a highly specific antibody against Bcl2 Ser87
Modification(s)Phosphorylation
Modification site(s)Ser87
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human Bcl2 around the phosphorylation site of Ser87
Gene ID number596
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also interacts with APAF1, BAD, BAK and BclX(L), BBC3, BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1), BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells, BCL2L1 and BNIPL, Constitutive expression of BCL2, Heterodimerization with BAX requires intact BH1 and BH2 domains, It appears to function in a feedback loop system with caspases, It can form homodimers, It regulates cell death by controlling the mitochondrial membrane permeability, RAF1, TP53BP2, Two transcript variants (alpha and beta) produced by alternate splicing, and heterodimers with BAX, and is necessary for anti-apoptotic activity, differ in their C-terminal ends, is thought to be the cause of follicular lymphoma, such as in the case of translocation of BCL2 to Ig heavy chain locus, BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 2, AW986256, Apoptosis regulator Bcl 2, Apoptosis regulator Bcl-2, Apoptosis regulator Bcl2, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, B cell lymphoma 2, B-cell, BCL2 protein, BCL2_HUMAN, Bcl 2, Bcl-2, Bcl2, Bcl2 phospho Ser87, C430015F12Rik, D630044D05Rik, D830018M01Rik, Leukemia/lymphoma, Oncogene B-cell leukemia 2, p-Bcl2 Ser87, p-Bcl2 phospho S87, Bcl2 phospho S87
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetBcl2 (Ser87)
Short nameBcl2 (Ser87) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameB-cell CLL/lymphoma 2 (Ser87) (Antibody to)
Alternative techniqueantibodies

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