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BCR Antibody / Breakpoint cluster region protein

BCR Antibody / Breakpoint cluster region protein size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenBCR / Breakpoint cluster region protein
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Added buffer025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2
Intented useThis BCR antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P11274
PurityAntigen affinity
Description A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, Although the BCR-ABL fusion protein has been extensively studied, The chromosome 22 breakpoint for this translocation is located within the BCR gene, The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac, The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, Two transcript variants encoding different isoforms have been found for this gene, the function of the normal BCR gene product is not clear, the gene at the chromosome 9 breakpoint, which is often found in patients with chronic myelogenous leukemia, The breakpoint cluster region protein (BCR) is a protein that in humans is encoded by the BCR gene
ImmunogenAmino acids M1-A100 from the human protein were used as the immunogen for the BCR antibody
Storage After reconstitution, Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, store at 4oC, the BCR antibody may be kept for up to one month refrigerated at +4 degrees C, For long-term, Prior to reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetBCR / Breakpoint cluster region protein
Short nameBCR Antibody / Breakpoint cluster region protein
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBCR (Antibody to) / Breakpoint cluster region protein
Alternative techniqueantibodies
Identity 1014
Gene BCR
Long gene name BCR, RhoGEF and GTPase activating protein
Synonyms gene D22S11 BCR1
Synonyms gene name breakpoint cluster region
Synonyms D22S662 CML PHL ALL
Locus 22q11, 23
Discovery year 1986-01-01
Entrez gene record 613
Pubmed identfication 1657398 18070886
RefSeq identity NM_004327
Classification Rho guanine nucleotide exchange factors Pleckstrin homology domain containing C2 domain containing
Havana BLAST/BLAT OTTHUMG00000150655
Locus Specific Databases LRG_1112

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