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Bcr (Tyr360) Antibody, Biotin Conjugated

Bcr (Tyr360) Antibody, Biotin Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Biotin Conjugated, Bcr (Tyr360) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBcr Tyr360
SpecificityThis is a highly specific antibody against Bcr Tyr360
ModificationPhosphorylation
Modification siteTyr360
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human Bcr around the phosphorylation site of Tyr360 [TT(p-Y)RM]
Gene ID number613
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Although the BCR-ABL fusion protein has been extensively studied, The chromosome 22 breakpoint for this translocation is located within the BCR gene, The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac, The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, Two transcript variants encoding different isoforms have been found for this gene, the function of the normal BCR gene product is not clear, the gene at the chromosome 9 breakpoint, which is often found in patients with chronic myelogenous leukemia, A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms ALL, BCR 1, BCR/ABL FUSION GENE INCLUDED, BCR/FGFR1 FUSION GENE INCLUDED, BCR/PDGFRA FUSION GENE INCLUDED, BCR1, BCR_HUMAN, Bcrphospho Y360, CML, P-Bcrphospho Y360, PHL, breakpoint cluster region, Bcr phospho Y360
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetBcr (Tyr360) Conjugated
Short name Conjugated, Bcr (Tyr360) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Bcr (Tyr360) (Antibody to)
Alternative techniqueantibodies

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