Name : Bcr (Tyr360) Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN5546553831
| Long name | Biotin Conjugated, Bcr (Tyr360) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Bcr Tyr360 |
| Specificity | This is a highly specific antibody against Bcr Tyr360 |
| Modification | Phosphorylation |
| Modification site | Tyr360 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human Bcr around the phosphorylation site of Tyr360 [TT(p-Y)RM] |
| Gene ID number | 613 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Although the BCR-ABL fusion protein has been extensively studied, The chromosome 22 breakpoint for this translocation is located within the BCR gene, The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac, The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, Two transcript variants encoding different isoforms have been found for this gene, the function of the normal BCR gene product is not clear, the gene at the chromosome 9 breakpoint, which is often found in patients with chronic myelogenous leukemia, A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | ALL, BCR 1, BCR/ABL FUSION GENE INCLUDED, BCR/FGFR1 FUSION GENE INCLUDED, BCR/PDGFRA FUSION GENE INCLUDED, BCR1, BCR_HUMAN, Bcrphospho Y360, CML, P-Bcrphospho Y360, PHL, breakpoint cluster region, Bcr phospho Y360 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Bcr (Tyr360) Conjugated |
| Short name | Conjugated, Bcr (Tyr360) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, Bcr (Tyr360) (Antibody to) |
| Alternative technique | antibodies |