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Bestrophin 2 Antibody

Bestrophin 2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBestrophin 2 Primary Polyclonal Antibody
Also known asBestrophin 2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBestrophin 2
SpecificityThis is a highly specific antibody against Bestrophin 2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Bestrophin 2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 1 also known as Best disease, 3 and 4, Bestrophin 2, Bestrophins were originally defined as a family of over 20 related sequences of the C, Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels, It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac), PR65, RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon, Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein, Three more members of the bestrophin family members were cloned and indentified recently, elegans, was confirmed by reciprocal immunoprecipitation, The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BEST2, BEST2_HUMAN, Best disease Bestrophin, Bestrophin2, FLJ20132, VMD2, VMD2 like gene 1, VMD2L1, Vitellorm macular dystrophy, Vitellorm macular dystrophy 2 homolog, Vitellorm macular dystrophy 2 like 1, Vitellorm macular dystrophy 2 like protein 1, BEST 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetBestrophin 2
Short nameBestrophin 2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBestrophin 2 (Antibody to)
Alternative techniqueantibodies
Identity 17106
Gene BEST4
Long gene name bestrophin 4
Synonyms gene VMD2L2
Synonyms gene name vitelliform macular dystrophy 2-like 2
Locus 1p34, 1
Discovery year 2003-12-03
GenBank acession AF440757
Entrez gene record 266675
Pubmed identfication 12032738 16702355
RefSeq identity NM_153274
Classification Bestrophins
Havana BLAST/BLAT OTTHUMG00000008488

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