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Bestrophin Antibody, ALEXA FLUOR 350

Bestrophin Antibody, ALEXA FLUOR 350 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 350 Conjugated, Bestrophin Polyclonal Antibody
Also known asAnti-Bestrophin PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBestrophin
SpecificityThis is a highly specific antibody against Bestrophin
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Bestrophin
Gene ID Number5068
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Best disease is frequently a reflection of mutations in the Bestrophin gene, Bestrophin Bestrophin 2, Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium, Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision, known as Best disease, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells, Best vitelliform macular dystrophy, Bestrophin 3
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetBestrophin
Short nameBestrophin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, Bestrophin (Antibody to)
Alternative techniqueantibodies
Identity 17106
Gene BEST4
Long gene name bestrophin 4
Synonyms gene VMD2L2
Synonyms gene name vitelliform macular dystrophy 2-like 2
Locus 1p34, 1
Discovery year 2003-12-03
GenBank acession AF440757
Entrez gene record 266675
Pubmed identfication 12032738 16702355
RefSeq identity NM_153274
Classification Bestrophins
Havana BLAST/BLAT OTTHUMG00000008488

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