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Beta Catenin Antibody (pS33/37)

Beta Catenin Antibody (pS33/37) size: 0.05 ml 199

Supplier NJS POLY
Price 199
Size 0.05 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenBeta Catenin (pS33/37)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutionsWestern blot: 1:500-1000
Intented useThis phospho-beta-Catenin antibodyis to be used only for research purposes and not for diagnostics
Gene ID #1499
Uniprot #P35222
PurityAntigen affinity
Description APC, AXIN2, Acts as a negative regulator of centrosome cohesion, Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome, CTNNB1 is not ubiquitinated and accumulates in the nucleus, Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML, In the absence of Wnt, In the presence of Wnt ligand, Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization, Involved in the regulation of cell adhesion, Promotes neurogenesis by maintaining sympathetic neuroblasts within the cell cycle (By similarity), forms a complex with AXIN1, leading to activate Wnt responsive genes, where it acts as a coactivator for transcription factors of the TCF/LEF family, Key downstream component of the canonical Wnt signaling pathway
ImmunogenA synthetic peptide corresponding to amino acids surrounding pS33 and pS37 from the human protein was used as the immunogen for the phospho-beta-Catenin antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-beta-Catenin antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetBeta Catenin (pS33/37)
Short nameBeta Catenin Antibody (pS33/37)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameb Catenin (Antibody to) (pS33/37)
Alternative techniqueantibodies

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