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Beta Catenin (Thr41 + Ser45) Antibody

Beta Catenin (Thr41 + Ser45) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBeta Catenin (Thr41 + Ser45) Antibody
Also known asBeta Catenin (Thr41 + Ser45) Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBeta Catenin Thr41 + Ser45
Specificity This phophorylation site is homologous to that of Thr41 + Ser45 in Mouse and Rat, This is a highly specific antibody against Beta Catenin Thr41 + Ser45
Modification(s)Phosphorylation
Modification site(s)Thr41 + Ser45
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range20-70/781
Subcellular location Cell membrane, Nucleus, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human Beta-Catenin around the phosphorylation site of Thr41/Ser45
Gene ID number1499
Swiss ProtP35222
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen APC, AXIN2, Acts as a negative regulator of centrosome cohesion, Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome, CTNNB1 is not ubiquitinated and accumulates in the nucleus, Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML, In the absence of Wnt, In the presence of Wnt ligand, Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization, Involved in the regulation of cell adhesion, forms a complex with AXIN1, leading to activate Wnt responsive genes, where it acts as a coactivator for transcription factors of the TCF/LEF family, Key downstream component of the canonical Wnt signaling pathway
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Beta-catenin, CTNNB1, Catenin beta-1, MRD19, OK/SW-cl, PRO2286, armadillo, 35, CTNNB
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetBeta Catenin (Thr41 + Ser45)
Short nameBeta Catenin (Thr41 + Ser45) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameb Catenin (Thr41 and Ser45) (Antibody to)
Alternative techniqueantibodies

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