Name : BFSP2/Phakinin Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8773597854
| Long name | BFSP2/Phakinin Primary Polyclonal Antibody |
| Also known as | BFSP2/Phakinin PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | BFSP2/Phakinin |
| Specificity | This is a highly specific antibody against BFSP2/Phakinin |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BFSP2/Phakinin |
| Gene ID number | 3921 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | IFs are cytoskeletal structures that typically contain a head, Mutations in the gene encoding Phakinin can result in lens cataract, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens, Phakinin copolymerizes with Filensin, Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles, Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens, Unlike most IFs, another IF protein, rod and tail domain, to form the 10-nm filamentous structures of the beaded filaments, Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 49 kD, BFSP2, BFSP2_HUMAN, Beaded filament protein CP49, Beaded filament structural protein 2, Beaded filament structural protein 2, Bfps2, CP47, CP49, Cytoskeletal protein, LL-L, Lens fiber cell beaded filament protein CP 47, Lens fiber cell beaded filament protein CP 49, PHAKOSIN, Phakinin, phakinin, 49 kDa cytoskeletal protein, Lens intermediate filament-like light |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | BFSP2/Phakinin |
| Short name | BFSP2/Phakinin Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | BFSP2/Phakinin (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1041 |
| Gene | BFSP2 |
| Long gene name | beaded filament structural protein 2 |
| Synonyms gene name | beaded filament structural protein 2, phakinin |
| Synonyms | CP47 CP49 LIFL-L phakinin |
| Locus | 3q22, 1 |
| Discovery year | 1999-04-14 |
| GenBank acession | U48224 |
| Entrez gene record | 8419 |
| Classification | Beaded filament structural proteins |
| Havana BLAST/BLAT | OTTHUMG00000159719 |
| Locus Specific Databases | Human Intermediate Filament Mutation Database |