Name : BFSP2/Phakinin Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN4100817484
| Long name | Biotin Conjugated, BFSP2/Phakinin Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | BFSP2/Phakinin |
| Specificity | This is a highly specific antibody against BFSP2/Phakinin |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human BFSP2/Phakinin |
| Gene ID number | 3921 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | IFs are cytoskeletal structures that typically contain a head, Mutations in the gene encoding Phakinin can result in lens cataract, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens, Phakinin copolymerizes with Filensin, Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles, Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens, Unlike most IFs, another IF protein, rod and tail domain, to form the 10-nm filamentous structures of the beaded filaments, Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | CP47 CP49 LIFL-L phakinin |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | BFSP2/Phakinin Conjugated |
| Short name | Conjugated, BFSP2/Phakinin Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, BFSP2/Phakinin (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1041 |
| Gene | BFSP2 |
| Long gene name | beaded filament structural protein 2 |
| Synonyms gene name | beaded filament structural protein 2, phakinin |
| Locus | 3q22, 1 |
| Discovery year | 1999-04-14 |
| GenBank acession | U48224 |
| Entrez gene record | 8419 |
| Classification | Beaded filament structural proteins |
| Havana BLAST/BLAT | OTTHUMG00000159719 |
| Locus Specific Databases | Human Intermediate Filament Mutation Database |