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BHLHB5 Antibody

BHLHB5 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBHLHB5 Primary Polyclonal Antibody
Also known asBHLHB5 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBHLHB5
SpecificityThis is a highly specific antibody against BHLHB5
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range255-305/381
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BHLHB5
Gene ID number27319
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen BETA 3 contains a putative DNA-binding domain, BETA 3 is a protein that is functionally similar to members of the Id family in that it can inhibit the binding of E47 homodimers as well as E47/Neuro D and E47/Myo D heterodimers to consensus DNA sequences , Class A proteins heterodimerize with class B proteins to activate transcription, Class A proteins include the ubiquitously expressed E-box binding factors E12/E47, Class B proteins such as Myo D, For instance, ITF2 and HEB (BETA 1 or HTF4), In contrast to members of the Id family, The Id family can therefore form heterodimers with the myogenic family, Working in opposition to these positively acting factors are a specialized group of proteins that function as dominant negative regulators, but the resulting complexes are transcriptionally inactive, myogenin and Neuro D (BETA 2) are transiently expressed and exhibit a more limited tissue distribution, the Id family of transcriptional repressors contains a HLH region required for dimerization but lacks a functional DNA-binding domain, Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BHE22_HUMAN, Beta3, CAGL85, Class B basic helix-loop-helix protein 5, Class E basic helix-loop-helix protein 22, Class II bHLH protein BHLHB5, TNRC20, Trinucleotide repeat containing 20, Trinucleotide repeat-containing gene 20 protein, bHLHB5, bHLHe22, Basic helix loop helix protein 5
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetBHLHB5
Short nameBHLHB5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBHLHB5 (Antibody to)
Alternative techniqueantibodies
Identity 11963
Gene BHLHE22
Long gene name basic helix-loop-helix family member e22
Synonyms gene TNRC20 BHLHB5
Synonyms gene name 5 basic helix-loop-helix family, class B, member e22 , trinucleotide repeat containing 20 basic helix-loop-helix domain containing
Synonyms CAGL85 Beta3 bHLHe22
Locus 8q12, 3
Discovery year 2000-01-27
GenBank acession U80755
Entrez gene record 27319
Pubmed identfication 9225980 12213201 18557763
RefSeq identity NM_152414
Classification Basic helix-loop-helix proteins Trinucleotide repeat containing
Havana BLAST/BLAT OTTHUMG00000164386

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