Name : BHLHB5 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN5295747756
| Long name | Biotin Conjugated, BHLHB5 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | BHLHB5 |
| Specificity | This is a highly specific antibody against BHLHB5 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 255-305/381 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic peptide derived from human BHLHB5 |
| Gene ID number | 27319 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | BETA 3 contains a putative DNA-binding domain, BETA 3 is a protein that is functionally similar to members of the Id family in that it can inhibit the binding of E47 homodimers as well as E47/Neuro D and E47/Myo D heterodimers to consensus DNA sequences , Class A proteins heterodimerize with class B proteins to activate transcription, Class A proteins include the ubiquitously expressed E-box binding factors E12/E47, Class B proteins such as Myo D, For instance, ITF2 and HEB (BETA 1 or HTF4), In contrast to members of the Id family, The Id family can therefore form heterodimers with the myogenic family, Working in opposition to these positively acting factors are a specialized group of proteins that function as dominant negative regulators, but the resulting complexes are transcriptionally inactive, myogenin and Neuro D (BETA 2) are transiently expressed and exhibit a more limited tissue distribution, the Id family of transcriptional repressors contains a HLH region required for dimerization but lacks a functional DNA-binding domain, Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | CAGL85 Beta3 bHLHe22 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | BHLHB5 Conjugated |
| Short name | Conjugated, BHLHB5 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, BHLHB5 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11963 |
| Gene | BHLHE22 |
| Long gene name | basic helix-loop-helix family member e22 |
| Synonyms gene | TNRC20 BHLHB5 |
| Synonyms gene name | 5 basic helix-loop-helix family, class B, member e22 , trinucleotide repeat containing 20 basic helix-loop-helix domain containing |
| Locus | 8q12, 3 |
| Discovery year | 2000-01-27 |
| GenBank acession | U80755 |
| Entrez gene record | 27319 |
| Pubmed identfication | 9225980 12213201 18557763 |
| RefSeq identity | NM_152414 |
| Classification | Basic helix-loop-helix proteins Trinucleotide repeat containing |
| Havana BLAST/BLAT | OTTHUMG00000164386 |